Since fevers are one of the organism's main tools for successfully defeating acute infections, fever-range whole-body hyperthermia has traditionally been used as one basic module in the treatment of chronic infections.
It can also be applied in chronic health problems after a disturbed convalescence of an acute infection, e.g., an infectious mononucleosis. Chronic infection with borrelia (Lyme disease) is described as a cause of most severe health problems, but it is very difficult in diagnosis and treatment. In-vitro studies showed that some borrelia strains have a heat sensitivity and are more susceptible to antibiotic drug treatment under elevated temperatures (Reisinger et al 1996). In severe cases resistant to any other therapies, even extreme WBH can be used.
